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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

4361

Name

MRE11A

Synonym

ATLD|HNGS1|MRE11|MRE11B;MRE11 meiotic recombination 11 homolog A (S. cerevisiae);MRE11A;MRE11 meiotic recombination 11 homolog A (S. cerevisiae)

Definition

AT-like disease|DNA recombination and repair protein|MRE11 homolog 1|MRE11 homolog A|double-strand break repair protein MRE11A|endo/exonuclease Mre11|meiotic recombination 11 homolog 1|meiotic recombination 11 homolog A

Position

11q21

Gene Type

protein-coding

Pathways and Diseases

Pathway

Non-homologous end-joining;KEGG PATHWAY;hsa03450

Pathway

Regulation of Telomerase;PID Curated;200072

Pathway

BARD1 signaling events;PID Curated;200174

Pathway

Homologous recombination;KEGG PATHWAY;hsa03440

Pathway

DNA Repair;Reactome;REACT:216

Pathway

role of brca1 brca2 and atr in cancer susceptibility;PID BioCarta;100234

Pathway

Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks;PID Reactome;500950

Disease

Colon cancer;FunDO

Disease

Adenovirus infection;FunDO

Disease

Stomach cancer;FunDO

Disease

Adenoma;FunDO

Disease

Leukoencephalopathy;FunDO

Disease

Ataxia telangiectasia;FunDO

Disease

Immune system diseases;KEGG DISEASE

Disease

Ataxia-telangiectasia-like disorder;OMIM

Disease

Lung cancer;FunDO

Disease

DNA repair defect;KEGG DISEASE;H00094

Disease

Hodgkin's disease;FunDO

Disease

Breast cancer;FunDO

Disease

Primary immunodeficiency;KEGG DISEASE

Disease

Alzheimer's disease;FunDO

External Links

Links to cell senescence gene database

4361

Links to epithelial mesenchymal transition gene database

4361

Links to ovarian cancer gene database

4361

Links to endometrial cancer gene database

4361

Links to iHOP

4361

Sequence Information

Nucleotide Sequence

>4361 : length: 5344
ACGTTATCCATGAAGTGTCGCGAGAGAAACGGACGCCGTTCTCTCCCGCGGAATTCAGGT
TTACGGCCCTGCGGGTTCTCAGAGGCAAGTTCAGACCGTGTTGTTTTCTTTTCACGGATC
CTGCCCTTTCTTCCCGAAAAGAAGACAGCCTTGGGTCGCGATTGTGGGGCTTCGAAGAGT
CCAGCAGTGGGAATTTCTAGAATTTGGAATCGAGTGCATTTTCTGACATTTGAGTACAGT
ACCCAGGGGTTCTTGGAGAAGAACCTGGTCCCAGAGGAGCTTGACTGACCATAAAAATGA
GTACTGCAGATGCACTTGATGATGAAAACACATTTAAAATATTAGTTGCAACAGATATTC
ATCTTGGATTTATGGAGAAAGATGCAGTCAGAGGAAATGATACGTTTGTAACACTCGATG
AAATTTTAAGACTTGCCCAGGAAAATGAAGTGGATTTTATTTTGTTAGGTGGTGATCTTT
TTCATGAAAATAAGCCCTCAAGGAAAACATTACATACCTGCCTCGAGTTATTAAGAAAAT
ATTGTATGGGTGATCGGCCTGTCCAGTTTGAAATTCTCAGTGATCAGTCAGTCAACTTTG
GTTTTAGTAAGTTTCCATGGGTGAACTATCAAGATGGCAACCTCAACATTTCAATTCCAG
TGTTTAGTATTCATGGCAATCATGACGATCCCACAGGGGCAGATGCACTTTGTGCCTTGG
ACATTTTAAGTTGTGCTGGATTTGTAAATCACTTTGGACGTTCAATGTCTGTGGAGAAGA
TAGACATTAGTCCGGTTTTGCTTCAAAAAGGAAGCACAAAGATTGCGCTATATGGTTTAG
GATCCATTCCAGATGAAAGGCTCTATCGAATGTTTGTCAATAAAAAAGTAACAATGTTGA
GACCAAAGGAAGATGAGAACTCTTGGTTTAACTTATTTGTGATTCATCAGAACAGGAGTA
AACATGGAAGTACTAACTTCATTCCAGAACAATTTTTGGATGACTTCATTGATCTTGTTA
TCTGGGGCCATGAACATGAGTGTAAAATAGCTCCAACCAAAAATGAACAACAGCTGTTTT
ATATCTCACAACCTGGAAGCTCAGTGGTTACTTCTCTTTCCCCAGGAGAAGCTGTAAAGA
AACATGTTGGTTTGCTGCGTATTAAAGGGAGGAAGATGAATATGCATAAAATTCCTCTTC
ACACAGTGCGGCAGTTTTTCATGGAGGATATTGTTCTAGCTAATCATCCAGACATTTTTA
ACCCAGATAATCCTAAAGTAACCCAAGCCATACAAAGCTTCTGTTTGGAGAAGATTGAAG
AAATGCTTGAAAATGCTGAACGGGAACGTCTGGGTAATTCTCACCAGCCAGAGAAGCCTC
TTGTACGACTGCGAGTGGACTATAGTGGAGGTTTTGAACCTTTCAGTGTTCTTCGCTTTA
GCCAGAAATTTGTGGATCGGGTAGCTAATCCAAAAGACATTATCCATTTTTTCAGGCATA
GAGAACAAAAGGAAAAAACAGGAGAAGAGATCAACTTTGGGAAACTTATCACAAAGCCTT
CAGAAGGAACAACTTTAAGGGTAGAAGATCTTGTAAAACAGTACTTTCAAACCGCAGAGA
AGAATGTGCAGCTCTCACTGCTAACAGAAAGAGGGATGGGTGAAGCAGTACAAGAATTTG
TGGACAAGGAGGAGAAAGATGCCATTGAGGAATTAGTGAAATACCAGTTGGAAAAAACAC
AGCGATTTCTTAAAGAACGTCATATTGATGCCCTCGAAGACAAAATCGATGAGGAGGTAC
GTCGTTTCAGAGAAACCAGACAAAAAAATACTAATGAAGAAGATGATGAAGTCCGTGAGG
CTATGACCAGGGCCAGAGCACTCAGATCTCAGTCAGAGGAGTCTGCTTCTGCCTTTAGTG
CTGATGACCTTATGAGTATAGATTTAGCAGAACAGATGGCTAATGACTCTGATGATAGCA
TCTCAGCAGCAACCAACAAAGGAAGAGGCCGAGGAAGAGGTCGAAGAGGTGGAAGAGGGC
AGAATTCAGCATCGAGAGGAGGGTCTCAAAGAGGAAGAGCAGACACTGGTCTGGAGACTT
CTACCCGTAGCAGGAACTCAAAGACTGCTGTGTCAGCATCTAGAAATATGTCTATTATAG
ATGCCTTTAAATCTACAAGACAGCAGCCTTCCCGAAATGTCACTACTAAGAATTATTCAG
AGGTGATTGAGGTAGATGAATCAGATGTGGAAGAAGACATTTTTCCTACCACTTCAAAGA
CAGATCAAAGGTGGTCCAGCACATCATCCAGCAAAATCATGTCCCAGAGTCAAGTATCGA
AAGGGGTTGATTTTGAATCAAGTGAGGATGATGATGATGATCCTTTTATGAACACTAGTT
CTTTAAGAAGAAATAGAAGATAATATATTTAATGGCACTGAGAAACATGCAAGATACAGG
AAAAATGAAAATGTTACAAGCTAAGAGTTTACAGTTTAAGATTTTAAGTATTGTTTCCTG
AGCATAACTCCATAAGTAAGAAATTTCTAGTTCACAGACATACAATAGCATTGATTCACC
TTGTTTTTTTAACCTGGTTGTTGTAGTAAGAGCTTTGTTTCAATATCACTCTTGAGTAAA
GATTAAAATAAAGCTACCATTTTACATTTCTATTTCATAATGAAAAACTATGTCAGTATT
TTAATATGGTTACATTTAGCCAAAGTTGAGGGAAAGAGCTTATAAAATTTAACTTCTTCA
TAATTTTAGTAATTTCCTAGAGGTTCTGGGTTTTCTGAAAGTAAAACAATTTATGCGAAC
CTATGTCTAAATTCACTGTTTGTTACTATGTATGTTTTTTTCCAATGCTTCTTATAAGAC
TAAATGATTAGAAGTACCTAATAGTTTGAACAGATATGTTTTTATTTAAAAGAGTAGAAT
AACCTTTCAGAATTACTGAGTTTTTTATTCCAGTTGTAGCAAAGATTTCAAAAGATTGTG
TTCCCATTAAGTGGTAGTAATTTCCTTTATTATTCTGTATCCTTAATGGTGTTCTCTCTC
TCTCTCTCTCTCTCTCTCTCTCCCTCTCCCCCCCGTTCCCCACTCTTCCTTTCTCCTTTG
CTTTTTCTTCTCTTTCATACATATATGCGTGCCTAGTTCTAGGAGGAAACGGGTTAAAAA
TTGTTTTAAACTACATCTTGAAAATATTGAAGAATTTGTTTTAGGTAGAGTGGTCAGTTG
AACCTTACAGTAAAGTATAGAAATATATTTAATGTGGAATGTCAATGCCAGGATTTCTCA
TTAACAATATTTTATCTCAACTTTGGTTCCTGTGATACATTTCTGAATGGGCAATTCCAG
AAATCTTAGTAGCCCATGTTAAGCTTCTATTTTTTACTTGTTTTCGGGGAGAAATAAGAA
TTAGACATCTTCAGATTTAAGTTAAATAATCCCATTCTTTATAATCCTCTGTAAAAAGAT
CCCTGAGATTATTCCTTCTTCTAGTTTTATGCGACAGCTTTACTTTAAAATTCAAGTTAT
ACATCTTGGGAGTACAATGGCCCGACATTTCTTCATAGGTAGAAACAAATACTTGACTCA
GTGATACTCATGACCATTAGAATAGTCATACCTGGAATGTGTCAAATTATAAGAGACAGA
CACTTGGTTAGTGGCTGCCTCATATAGCACTTTTGAAGAGGCCTAAGTCAAAACTTGCAA
TATAACATTCTATTGACTTTCTTAAAAATATTTTTTCTGTACCTAACTTGAGCATAAGGG
TTATTTGAGCAAGTAACATTAACTCAGTGGAAGGCATTGTCCTGTGAAATATTCTTAGGC
AGATCTGCCCACATCTTTATTGAACTTGAAATCTAATATTTCTAGTATTTGAACAAAGCA
GAAGGTTAAGTCAGGGAAGAGCAGTGCTGTCCATGATGTAATGGAAGCTACCAGGGGAGG
CAGTGTCTGGATGATGCTGTGCTACCTACCCCTGCACAAGCCATGCTGGCTCAGTCTGAG
CTGTGGGCCACATCAGCTAGTGGCTCTTCTCATGCATCAGTTAGGTGGGTCTGGGTGAGA
GTTATAGTGAGGGAATGGTCACTAAAGTATCCTGACAAGTTCCTAGGAAAAAAGGAATAA
AGTTTTTTTCCTTAAAAAAAAAAAAATTGCTCTTGGCTGTGAAAAGAGGTACTAAATGCG
ATTCAGTTCACCGCTAAGGAAAGTGATGACATAGCAGTTACAGAGGGTGATAAATCTCTC
CAGCTAATTCAGGTCATTTTGTGAATACTATGTATCAAGCCCTGAAAATATGGTAAATAA
AACGTGACAGGGAAACCTTTTTTTGATTGAATATTGTTACATAGTTAAATGTGCTATATA
TCCTTAATATTTTATATTGATCCTGCAAAATCTGTTGGTTTTAGGGGAGTTTTGTTTTTT
GTTTCTAACAATTTTCAGACCTGTTGGTATAGGAATGTAGAAGTCTTTCAGATGATTTGA
AAGCAGCTGCATTTGCTCTTGGAGGCTTTGGGAGAGCAGGAATGAAAACATTCAGAGGAA
GACATCTGTAGGGAATTCTTCTGTTACTTACCAAAGAATAAGTGTCTTTCTGGTGTTTTA
TTTCCTATCATAAAAATACAACAGTGCATTTACAAGGTTAAAGATTCCTCGAAGTTCTAG
GAAATTCTTGAAAATATAAGTGGTGCTTAGAAAATTCAAGCATTTAGGAATGTGACCTTT
AATTCAGGAACACGTTTCTCCAATTACTGTTGGCAAGACTACCAAGAAAAATTGTTGAAT
TAGAATCCCAGCACCGGGCACGGTGGCTCACGCCTGTGATCCTAGCACTTTGGGAGGCCA
AAGCAGGCGGATCACCTGAGGTCAGGAGTTCGAGACCAGCAGGGCCAACATGGCGAAACC
CCGACTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGTGGGCGCCTGTAATCCCAA
CTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGTTGGAGGTCACGGTGAG
CTGATATCACGCCATTGCACTCCAGCCTGGGCAACAGAGCAAGACTCTGTCTCAATCAAT
CTATCCATCAATCGATAAGAACCCCAGATTGTATAGCTACATGTTTTAGCCCCCTTTTCA
AAGTATATGTTCTCCTTGGTACTTATTTTGACATTCTGACTTTTCTACATATGCTTTATC
AACCTCTTAATTAAACCATCATTGTCTATTTTGAGAGATAACTGCGCTGCTTCCCGTTGT
GTGTTTTAAATGTTATTGTTCAGTTTGAGTCAAATAAAAGGATATTTAATCTGTGGTGCC
TTGA

Protein Sequence

>4361 : length: 708
MSTADALDDENTFKILVATDIHLGFMEKDAVRGNDTFVTLDEILRLAQENEVDFILLGGD
LFHENKPSRKTLHTCLELLRKYCMGDRPVQFEILSDQSVNFGFSKFPWVNYQDGNLNISI
PVFSIHGNHDDPTGADALCALDILSCAGFVNHFGRSMSVEKIDISPVLLQKGSTKIALYG
LGSIPDERLYRMFVNKKVTMLRPKEDENSWFNLFVIHQNRSKHGSTNFIPEQFLDDFIDL
VIWGHEHECKIAPTKNEQQLFYISQPGSSVVTSLSPGEAVKKHVGLLRIKGRKMNMHKIP
LHTVRQFFMEDIVLANHPDIFNPDNPKVTQAIQSFCLEKIEEMLENAERERLGNSHQPEK
PLVRLRVDYSGGFEPFSVLRFSQKFVDRVANPKDIIHFFRHREQKEKTGEEINFGKLITK
PSEGTTLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLEK
TQRFLKERHIDALEDKIDEEVRRFRETRQKNTNEEDDEVREAMTRARALRSQSEESASAF
SADDLMSIDLAEQMANDSDDSISAATNKGRGRGRGRRGGRGQNSASRGGSQRGRADTGLE
TSTRSRNSKTAVSASRNMSIIDAFKSTRQQPSRNVTTKNYSEVIEVDESDVEEDIFPTTS
KTDQRWSSTSSSKIMSQSQVSKGVDFESSEDDDDDPFMNTSSLRRNRR