ONGene
Top
Scroll To Top
Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

331

Name

XIAP

Synonym

API3|BIRC4|IAP-3|ILP1|MIHA|XLP2|hIAP-3|hIAP3;X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase;XIAP;X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase

Definition

E3 ubiquitin-protein ligase XIAP|IAP-like protein|X-linked IAP|baculoviral IAP repeat-containing protein 4|inhibitor of apoptosis protein 3

Position

Xq25

Gene Type

protein-coding

Pathways and Diseases

Pathway

Apoptosis;Reactome;REACT:578

Pathway

TGF-beta receptor signaling;PID Curated;200195

Pathway

BMP receptor signaling;PID Curated;200123

Pathway

Focal adhesion;KEGG PATHWAY;hsa04510

Pathway

Pathways in cancer;KEGG PATHWAY;hsa05200

Pathway

NOD-like receptor signaling pathway;KEGG PATHWAY;hsa04621

Pathway

Apoptosis;KEGG PATHWAY;hsa04210

Pathway

Ubiquitin mediated proteolysis;KEGG PATHWAY;hsa04120

Pathway

SMAC binds to IAPs;PID Reactome;500884

Pathway

SMAC-mediated dissociation of IAP:caspase complexes;PID Reactome;500934

Pathway

Apoptosis signaling pathway;PANTHER;P00006

Pathway

Small cell lung cancer;KEGG PATHWAY;hsa05222

Pathway

Caspase cascade in apoptosis;PID Curated;200148

Pathway

Toxoplasmosis;KEGG PATHWAY;hsa05145

Disease

Lymphoproliferative syndrome, X-linked, 2;OMIM

Disease

Ischemia;FunDO

Disease

Other well-defined immunodeficiency syndromes;KEGG DISEASE;H00107

Disease

Immune system diseases;KEGG DISEASE

Disease

Copper metabolism disorder;FunDO

Disease

Multiple sclerosis;FunDO

Disease

Cancer;FunDO

Disease

Familial Mediterranean Fever;GAD

Disease

mevalonate kinase deficiency;GAD

Disease

Primary immunodeficiency;KEGG DISEASE

Disease

Immunologic deficiency syndrome;FunDO

Disease

Cryopyrin-associated Periodic Syndromes;GAD

External Links

Links to cell senescence gene database

331

Links to epithelial mesenchymal transition gene database

331

Links to ovarian cancer gene database

331

Links to endometrial cancer gene database

331

Links to iHOP

331

Sequence Information

Nucleotide Sequence

>331 : length: 8524
ATCCGGTTCGGGGAGGTGGCGGGACCTTGGCGGCGCCCGGAGCCGGCGTGGCGCTCATCG
AGGGACGCCCGGCCCAAGTGGCTGGGGCCAAGCCGCAGAGCGGAGTTGGCATTTCCAGAT
TGGGGCTCGGGCCGCGCCTCCTCCGGGACCCTCCCCTTGGACCGAGCCGATCGCCGCGGG
GCAGTTCGGGCCGGCTGTCCTGGCGCGAAAAGGTGGACAAGTCCTATTTTCAAGAGAAGA
TGACTTTTAACAGTTTTGAAGGATCTAAAACTTGTGTACCTGCAGACATCAATAAGGAAG
AAGAATTTGTAGAAGAGTTTAATAGATTAAAAACTTTTGCTAATTTTCCAAGTGGTAGTC
CTGTTTCAGCATCAACACTGGCACGAGCAGGGTTTCTTTATACTGGTGAAGGAGATACCG
TGCGGTGCTTTAGTTGTCATGCAGCTGTAGATAGATGGCAATATGGAGACTCAGCAGTTG
GAAGACACAGGAAAGTATCCCCAAATTGCAGATTTATCAACGGCTTTTATCTTGAAAATA
GTGCCACGCAGTCTACAAATTCTGGTATCCAGAATGGTCAGTACAAAGTTGAAAACTATC
TGGGAAGCAGAGATCATTTTGCCTTAGACAGGCCATCTGAGACACATGCAGACTATCTTT
TGAGAACTGGGCAGGTTGTAGATATATCAGACACCATATACCCGAGGAACCCTGCCATGT
ATAGTGAAGAAGCTAGATTAAAGTCCTTTCAGAACTGGCCAGACTATGCTCACCTAACCC
CAAGAGAGTTAGCAAGTGCTGGACTCTACTACACAGGTATTGGTGACCAAGTGCAGTGCT
TTTGTTGTGGTGGAAAACTGAAAAATTGGGAACCTTGTGATCGTGCCTGGTCAGAACACA
GGCGACACTTTCCTAATTGCTTCTTTGTTTTGGGCCGGAATCTTAATATTCGAAGTGAAT
CTGATGCTGTGAGTTCTGATAGGAATTTCCCAAATTCAACAAATCTTCCAAGAAATCCAT
CCATGGCAGATTATGAAGCACGGATCTTTACTTTTGGGACATGGATATACTCAGTTAACA
AGGAGCAGCTTGCAAGAGCTGGATTTTATGCTTTAGGTGAAGGTGATAAAGTAAAGTGCT
TTCACTGTGGAGGAGGGCTAACTGATTGGAAGCCCAGTGAAGACCCTTGGGAACAACATG
CTAAATGGTATCCAGGGTGCAAATATCTGTTAGAACAGAAGGGACAAGAATATATAAACA
ATATTCATTTAACTCATTCACTTGAGGAGTGTCTGGTAAGAACTACTGAGAAAACACCAT
CACTAACTAGAAGAATTGATGATACCATCTTCCAAAATCCTATGGTACAAGAAGCTATAC
GAATGGGGTTCAGTTTCAAGGACATTAAGAAAATAATGGAGGAAAAAATTCAGATATCTG
GGAGCAACTATAAATCACTTGAGGTTCTGGTTGCAGATCTAGTGAATGCTCAGAAAGACA
GTATGCAAGATGAGTCAAGTCAGACTTCATTACAGAAAGAGATTAGTACTGAAGAGCAGC
TAAGGCGCCTGCAAGAGGAGAAGCTTTGCAAAATCTGTATGGATAGAAATATTGCTATCG
TTTTTGTTCCTTGTGGACATCTAGTCACTTGTAAACAATGTGCTGAAGCAGTTGACAAGT
GTCCCATGTGCTACACAGTCATTACTTTCAAGCAAAAAATTTTTATGTCTTAATCTAACT
CTATAGTAGGCATGTTATGTTGTTCTTATTACCCTGATTGAATGTGTGATGTGAACTGAC
TTTAAGTAATCAGGATTGAATTCCATTAGCATTTGCTACCAAGTAGGAAAAAAAATGTAC
ATGGCAGTGTTTTAGTTGGCAATATAATCTTTGAATTTCTTGATTTTTCAGGGTATTAGC
TGTATTATCCATTTTTTTTACTGTTATTTAATTGAAACCATAGACTAAGAATAAGAAGCA
TCATACTATAACTGAACACAATGTGTATTCATAGTATACTGATTTAATTTCTAAGTGTAA
GTGAATTAATCATCTGGATTTTTTATTCTTTTCAGATAGGCTTAACAAATGGAGCTTTCT
GTATATAAATGTGGAGATTAGAGTTAATCTCCCCAATCACATAATTTGTTTTGTGTGAAA
AAGGAATAAATTGTTCCATGCTGGTGGAAAGATAGAGATTGTTTTTAGAGGTTGGTTGTT
GTGTTTTAGGATTCTGTCCATTTTCTTTTAAAGTTATAAACACGTACTTGTGCGAATTAT
TTTTTTAAAGTGATTTGCCATTTTTGAAAGCGTATTTAATGATAGAATACTATCGAGCCA
ACATGTACTGACATGGAAAGATGTCAAAGATATGTTAAGTGTAAAATGCAAGTGGCAAAA
CACTATGTATAGTCTGAGCCAGATCAAAGTATGTATGTTTTTAATATGCATAGAACAAAA
GATTTGGAAAGATATACACCAAACTGTTAAATGTGGTTTCTCTTCGGGGAGGGGGGGATT
GGGGGAGGGGCCCCAGAGGGGTTTTATAGGGGCCTTTTCACTTTCTACTTTTTTCATTTT
GTTCTGTTCGAATTTTTTATAAGTATGTATTACTTTTGTAATCAGAATTTTTAGAAAGTA
TTTTGCTGATTTAAAGGCTTAGGCATGTTCAAACGCCTGCAAAACTACTTATCACTCAGC
TTTAGTTTTTCTAATCCAAGAAGGCAGGGCAGTTAACCTTTTTGGTGCCAATGTGAAATG
TAAATGATTTTATGTTTTTCCTGCTTTGTGGATGAAAAATATTTCTGAGTGGTAGTTTTT
TGACAGGTAGACCATGTCTTATCTTGTTTCAAAATAAGTATTTCTGATTTTGTAAAATGA
AATATAAAATATGTCTCAGATCTTCCAATTAATTAGTAAGGATTCATCCTTAATCCTTGC
TAGTTTAAGCCTGCCTAAGTCACTTTACTAAAAGATCTTTGTTAACTCAGTATTTTAAAC
ATCTGTCAGCTTATGTAGGTAAAAGTAGAAGCATGTTTGTACACTGCTTGTAGTTATAGT
GACAGCTTTCCATGTTGAGATTCTCATATCATCTTGTATCTTAAAGTTTCATGTGAGTTT
TTACCGTTAGGATGATTAAGATGTATATAGGACAAAATGTTAAGTCTTTCCTCTACCTAC
ATTTGTTTTCTTGGCTAGTAATAGTAGTAGATACTTCTGAAATAAATGTTCTCTCAAGAT
CCTTAAAACCTCTTGGAAATTATAAAAATATTGGCAAGAAAAGAAGAATAGTTGTTTAAA
TATTTTTTAAAAAACACTTGAATAAGAATCAGTAGGGTATAAACTAGAAGTTTAAAAATG
CTTCATAGAACGTCCAGGGTTTACATTACAAGATTCTCACAACAAACCTATTGTAGAGGT
GAGTAAGGCATGTTACTACAGAGGAAAGTTTGAGAGTAAAACTGTAAAAAATTATATTTT
TGTTGTACTTTCTAAGAGAAAGAGTATTGTTATGTTCTCCTAACTTCTGTTGATTACTAC
TTTAAGTGATATTCATTTAAAACATTGCAAATTTATTTTATTTATTTAATTTTCTTTTTG
AGATGGAGTCTTGCTTGTCACCCAGGCTGGAGTGCAGTGGAGTGATCTCTGCTCACTGCA
ACCTCCGCCTTCTGGGTTCAAGCGATTCTCGTGCCTCAGCTTCCTGAGTAGCTGGAATTA
CAGGCAGGTGCCACCATGCCCGACTAATTTTTTTTTATTTTTAGTAGAGACGGGGTTTCA
CCATGTTGGCCAGGCTGGTATCAAACTCCTGACCTCAAGAGATCCACTCGCCTTGCCCTC
CCAAAGTGCTGGGATTACAGGCTTGAGCCACCACGCCCGGCTAAAACATTGCAAATTTAA
ATGAGAGTTTTAAAAATTAAATAATGACTGCCCTGTTTCTGTTTTAGTATGTAAATCCTC
AGTTCTTCACCTTTGCACTGTCTGCCACTTAGTTTGGTTATATAGTCATTAACTTGAATT
TGGTCTGTATAGTCTAGACTTTAAATTTAAAGTTTTCTACAAGGGGAGAAAAGTGTTAAA
ATTTTTAAAATATGTTTTCCAGGACACTTCACTTCCAAGTCAGGTAGGTAGTTCAATCTA
GTTGTTAGCCAAGGACTCAAGGACTGAATTGTTTTAACATAAGGCTTTTCCTGTTCTGGG
AGCCGCACTTCATTAAAATTCTTCTAAAACTTGTATGTTTAGAGTTAAGCAAGACTTTTT
TTCTTCCTCTCCATGAGTTGTGAAATTTAATGCACAACGCTGATGTGGCTAACAAGTTTA
TTTTAAGAATTGTTTAGAAATGCTGTTGCTTCAGGTTCTTAAAATCACTCAGCACTCCAA
CTTCTAATCAAATTTTTGGAGACTTAACAGCATTTGTCTGTGTTTGAACTATAAAAAGCA
CCGGATCTTTTCCATCTAATTCCGCAAAAATTGATCATTTGCAAAGTCAAAACTATAGCC
ATATCCAAATCTTTTCCCCCTCCCAAGAGTTCTCAGTGTCTACATGTAGACTATTCCTTT
TCTGTATAAAGTTCACTCTAGGATTTCAAGTCACCACTTATTTTACATTTTAGTCATGCA
AAGATTCAAGTAGTTTTGCAATAAGTACTTATCTTTATTTGTAATAATTTAGTCTGCTGA
TCAAAAGCATTGTCTTAATTTTTGAGAACTGGTTTTAGCATTTACAAACTAAATTCCAGT
TAATTAATTAATAGCTTTATATTGCCTTTCCTGCTACATTTGGTTTTTTCCCCTGTCCCT
TTGATTACGGGCTAAGGTAGGGTAGAGTGGGTGTAGTGAGTGTATATAATGTGATTTGGC
CCTGTGTATTATGATATTTTGTTATTTTTGTTGTTATATTATTTACATTTCAGTAGTTGT
TTTTTGTGTTTCCATTTTAGTGGATAAAATTTGTATTTTGAACTATGAATGGAGACTACC
GCCCCAGCATTAGTTTCACATGATATACCCTTTAAACCCGAATCATTGTTTTATTTCCTG
ATTACACAGGTGTTGAATGGGGAAAGGGGCTAGTATATCAGTAGGATATACTATGGGATG
TATATATATCATTGCTGTTAGAGAAATGAAATAAAATGGGGCTGGGCTCAGTGGCTCACG
CCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTGGATCACGAGGTCAGGAGATCGAG
ACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAAACAGAAAATTAGCCGGGC
GTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGTGTGA
ACCCGGGAGGCAGAGCTTGCAGTGAGCCGAGATCTCGCCACTGCACTCCAGCCTGGGCAA
CAGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAAAGAAATAAGAAAATGGGAAGCAATAT
TTGACATAGTTCTTTTTAGTCAAATCTACTTGTTAAAAAAAGGGTAGCAGTTTATTCATC
TGTGAAAGGAAAATAATACTTATCTTACAAGGTTGCAAGAGCTCAAGGAGACCATGTATG
TAAAGTTCCTGCTGTAAATATGAACTCCCATCCTAATACCCTTTTACCTCTCTGTGGGTT
TGTCTTGACCTGGAAATTTGGGCTAAAACTTAGAAAAAATTCTTACATGATAACTCAGTG
ATGCTTACTCATAGTTTTTGGTGTTTCTCATAGATAAGATATAAATCAGCTGGGCGCGGT
GGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGATCACCTGAGGTCG
GGAGGTCGAGACCAGCCTGACCAACATGGAGAAACCCCGTCTCTACTAAAAATACAAAAT
TAGCTGGGCGTGGTGGCTCATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGA
ATCGCTTGAACCCAGGAGGCGGAGGTTGTGGTGAGCGAAGATCGTGCCATTGCACTCCAG
CCTGGGCAACAAGAGCAAAACTCTGTCTCAAAAAAAAAAAAAGATATAAATCACAATAAA
TAAATAGGTCAATACAAATGTTAGCCAGGCGTGGTGGCACATGCCCATAGTCGCAGCTAC
TCTGGAGGCAGAGGCAGGAGGATCACTTGAGCCCATGAATTTGAGGCAGCAGTGAGCTAT
GATTGTGCCACTGTACTCCAGTCTGGGTGACAGAGTGAGACCCCATCTCTAAATAAATAG
GTCAAACCCTTAAAAATATTTAAATTCTTAAAAAATTGAAAAGATTATTCTTCTCAAATT
TAGTTGAGCTTTCTAAGAGAAGCAATTGGCTTTTTCCCACTTCAATAATCATTTTCAGTT
TGACTCATACAGTTAACACAATGTGAATTTCTTCCTCAGCATAACAGAGTTATAGAATGA
CAGGGCTGGAAGTGACCTTAGAGAGTATCCAGTTCTTTCATTTTACAGGTGAGGCAACTG
AGACTCAAAGGTGATGTAATTTGTGCAAAGATTATAGCTAATTAGTAGCAGAGCCCTGAC
TGGGACATAGTTTGAAGGTGAAAAACTTCACCAAGCTACCTTTCTTGAAAGGTCCAAATG
TTTATGTTTTCAACTACTCTTTCCACTGTACCATAACTTTCACTACATATTAAATGACAC
TTTATAACTAATATAATAGGACAATCATCAATGCATATATAGCCAGCCCTTCATATCTGT
GGGTTTTGCATCCATGGATTCAACCAAGGAGGAATTGAAAACACTGAGAAAAAAAAAAAA
GACCACACAATAAAAAAAAAAAATACAAAATAATACAAAGAAAAAGCCAAAATTGTCATA
CTGTTGTTAAGCAACAGTATAACAACTATTTACATAGCATTAAGGTTGGTGCAAAAATGC
AAAAAAAAAAAAAGCAATTATTTTTAAACCAACCTAATATATTGTATTAGGTATTAAAGT
CATCTGGACATGAATTAAAGTATATGATGCCAGCCTGGACAAAAGGCAAAACCCTGTCTC
TACAAAAAATACAAAAATTAGCTGGGCATGGTGGTGTGTGCCTGTAGTCCTGGCTACTCC
GGAGCCTGAGGTGGGAGGATCGCTTGAGTCTGGGAGGCAGAGGCTGCATTGAGCTATGAT
CATGGCACTGCATTCCAGCCTGGGTGACAGTGCAAGACCTTGTCTCAGAATAAATAAAGT
ATGTGATGAAGATGTGCATACATTATATGCAAATACTGTTTTTTTTTTTTTTAATTTAAA
CAGTCTCACTGTGTTGCCCAGGATGGAGTGCAATGGCACAATCTTGGCTCATGGCAAACT
CTGCCTCGCAAGCAGCTGGGACTACAGGCATGCTCCACGGTGCCCAGTTAATTTTTTTTG
TATTCTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTAGTCTTGAATTTCTGACCT
CAAGTGATTCATCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACGGCCGGCTAAT
TTTTGTATTTTTTAGTAGTGACTGGTTTCGCGGTGTTGACCAGGCTGGTCTCGAACTCCT
GATCTCAGGTGATCTGCCTGCCTCGGCCTCACAAAGTGCTGGGATTACAGGTGTGAACCA
CTGCTCCCGGCCTTGTGTGATTTTATCTAAGGGACTTAAGCGTCCTCAGGTCCTAGGGGG
TCGTGAAACCAAAACCCCAGGGATAGCAAGGGACAATTGTATCTTCAAAGTAGACAAATG
GCGCCGGGCACGGTGGCTCACGCCTGTAATCCCAGCAGTTTCCGAGGCTGAGGCAGGCGG
CTCACCTGAGGTCAGGAGTTGGAGACCAGCCTGGCCAACATGCTGAAACCCTGTCTGTAC
AAAAATACAAAAATAGCTGGGCATGGTGGCGCATGCCTGTAGTCCCAGCTACTAGAGCGA
CTGAGGCAGGAGAATTGCTTGAACCTGGGAGGCGGAGGTTGCAGGGAGCCAAGATGGCGC
CACCGCACTCCAGCCTAGGTGATAGAGTGAGACTCCCTCTCAAAAACAAAACAAAACAAA
AAAATTAGACAAATGCTACATTAATGTTTGGGTGGTCAGATTCTACTTTGAATCTGAAGT
TTGCAGATATGCCTATAGATTTTTGGAGTTTACCACTTTCTTATTCTGTATCATTAATGT
AATATTTTAAATTACTATATATGTTACCATTTTTCTGGATTTAGTAAGAAATTTGCAGTT
TTGGTTTGATGTAACAAGGGTTTTAATGTAATTTATGTTAGATTTTGCATTTTTTTCATT
ACTGTTATATTTTAACCTGACTGACTGATCTAATTGTATTAGTATTGTGAATAATCATGT
GAAATGTTTTGAGACAGAGTACTATATTTGTGAATATAATTTTATGGTTTTTTTCACTTA
GAACCTTTCTGTGTGGAAAACTAAGAAAATTGCTTTCTGCTGTATAATCTGGCATTCATT
GTAGATTAAAGCTTATTTTTCTGTGAATAAAACGTATTCAATAAAATACTATTCTTTAAA
ATTA

Protein Sequence

>331 : length: 497
MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDT
VRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENY
LGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLT
PRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSE
SDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKC
FHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTP
SLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKD
SMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDK
CPMCYTVITFKQKIFMS