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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

3265

Name

HRAS

Synonym

C-BAS/HAS|C-H-RAS|C-HA-RAS1|CTLO|H-RASIDX|HAMSV|HRAS1|RASH1|p21ras;Harvey rat sarcoma viral oncogene homolog;HRAS;Harvey rat sarcoma viral oncogene homolog

Definition

GTP- and GDP-binding peptide B|GTPase HRas|Ha-Ras1 proto-oncoprotein|Harvey rat sarcoma viral oncoprotein|Ras family small GTP binding protein H-Ras|c-has/bas p21 protein|c-ras-Ki-2 activated oncogene|p19 H-RasIDX protein|transformation gene: oncogene HAM

Position

11p15.5

Gene Type

protein-coding

Pathways and Diseases

Pathway

il-2 receptor beta chain in t cell activation;PID BioCarta;100129

Pathway

role of erbb2 in signal transduction and oncology;PID BioCarta;100147

Pathway

Signaling by Insulin receptor;Reactome;REACT:498

Pathway

Axon guidance;Reactome;REACT:18266

Pathway

MAPK signaling pathway;KEGG PATHWAY;hsa04010

Pathway

Endometrial cancer;KEGG PATHWAY;hsa05213

Pathway

insulin signaling pathway;PID BioCarta;100124

Pathway

TGF-beta signaling pathway;PANTHER;P00052

Pathway

pdgf signaling pathway;PID BioCarta;100077

Pathway

PDGFR-beta signaling pathway;PID Curated;200127

Pathway

sprouty regulation of tyrosine kinase signals;PID BioCarta;100029

Pathway

FGF signaling pathway;PANTHER;P00021

Pathway

Melanogenesis;KEGG PATHWAY;hsa04916

Pathway

Signaling by EGFR;Reactome;REACT:9417

Pathway

EPHB forward signaling;PID Curated;200041

Pathway

PDGF signaling pathway;PANTHER;P00047

Pathway

egf signaling pathway;PID BioCarta;100181

Pathway

aspirin blocks signaling pathway involved in platelet activation;PID BioCarta;100030

Pathway

EGF receptor signaling pathway;PANTHER;P00018

Pathway

regulation of splicing through sam68;PID BioCarta;100036

Pathway

inhibition of cellular proliferation by gleevec;PID BioCarta;100154

Pathway

Endothelins;PID Curated;200004

Pathway

Fc epsilon RI signaling pathway;KEGG PATHWAY;hsa04664

Pathway

how progesterone initiates the oocyte maturation;PID BioCarta;100104

Pathway

bcr signaling pathway;PID BioCarta;100227

Pathway

erk1/erk2 mapk signaling pathway;PID BioCarta;100170

Pathway

Bladder cancer;KEGG PATHWAY;hsa05219

Pathway

nfat and hypertrophy of the heart ;PID BioCarta;100098

Pathway

ccr3 signaling in eosinophils;PID BioCarta;100215

Pathway

tpo signaling pathway;PID BioCarta;100012

Pathway

mcalpain and friends in cell motility;PID BioCarta;100111

Pathway

Long-term depression;KEGG PATHWAY;hsa04730

Pathway

p53 pathway feedback loops 2;PANTHER;P04398

Pathway

trka receptor signaling pathway;PID BioCarta;100011

Pathway

role of egf receptor transactivation by gpcrs in cardiac hypertrophy;PID BioCarta;100221

Pathway

Syndecan-2-mediated signaling events;PID Curated;200164

Pathway

multiple antiapoptotic pathways from igf-1r signaling lead to bad phosphorylation;PID BioCarta;100135

Pathway

signaling pathway from g-protein families;PID BioCarta;100153

Pathway

Signaling events mediated by VEGFR1 and VEGFR2;PID Curated;200161

Pathway

BCR signaling pathway;PID Curated;200005

Pathway

Signaling by PDGF;Reactome;REACT:16888

Pathway

mapkinase signaling pathway;PID BioCarta;100113

Pathway

EGFR-dependent Endothelin signaling events;PID Curated;200095

Pathway

epo signaling pathway;PID BioCarta;100175

Pathway

mets affect on macrophage differentiation;PID BioCarta;100169

Pathway

B cell activation;PANTHER;P00010

Pathway

Prostate cancer;KEGG PATHWAY;hsa05215

Pathway

melanocyte development and pigmentation pathway;PID BioCarta;100108

Pathway

Angiogenesis;PANTHER;P00005

Pathway

phospholipids as signalling intermediaries;PID BioCarta;100183

Pathway

IGF1 pathway;PID Curated;200084

Pathway

Pathways in cancer;KEGG PATHWAY;hsa05200

Pathway

Thyroid cancer;KEGG PATHWAY;hsa05216

Pathway

Melanoma;KEGG PATHWAY;hsa05218

Pathway

Glioma;KEGG PATHWAY;hsa05214

Pathway

influence of ras and rho proteins on g1 to s transition;PID BioCarta;100054

Pathway

B cell receptor signaling pathway;KEGG PATHWAY;hsa04662

Pathway

Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722

Pathway

Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810

Pathway

fmlp induced chemokine gene expression in hmc-1 cells;PID BioCarta;100162

Pathway

trefoil factors initiate mucosal healing;PID BioCarta;100018

Pathway

a6b1 and a6b4 Integrin signaling;PID Curated;200162

Pathway

Ras activation uopn Ca2+ infux through NMDA receptor;PID Reactome;500178

Pathway

T cell receptor signaling pathway;KEGG PATHWAY;hsa04660

Pathway

Axon guidance;KEGG PATHWAY;hsa04360

Pathway

Nongenotropic Androgen signaling;PID Curated;200145

Pathway

transcription factor creb and its extracellular signals;PID BioCarta;100198

Pathway

Inflammation mediated by chemokine and cytokine signaling pathway;PANTHER;P00031

Pathway

Signalling by NGF;Reactome;REACT:11061

Pathway

CDC42 signaling events;PID Curated;200057

Pathway

Insulin Pathway;PID Curated;200012

Pathway

bioactive peptide induced signaling pathway;PID BioCarta;100226

Pathway

Long-term potentiation;KEGG PATHWAY;hsa04720

Pathway

CREB phophorylation through the activation of Ras;PID Reactome;500177

Pathway

keratinocyte differentiation;PID BioCarta;100119

Pathway

Synaptic Transmission;Reactome;REACT:13685

Pathway

angiotensin ii mediated activation of jnk pathway via pyk2 dependent signaling;PID BioCarta;100236

Pathway

Integrin signalling pathway;PANTHER;P00034

Pathway

ras signaling pathway;PID BioCarta;100047

Pathway

Renal cell carcinoma;KEGG PATHWAY;hsa05211

Pathway

cxcr4 signaling pathway;PID BioCarta;100192

Pathway

nerve growth factor pathway (ngf);PID BioCarta;100096

Pathway

Hemostasis;Reactome;REACT:604

Pathway

role of mal in rho-mediated activation of srf;PID BioCarta;100114

Pathway

vegf hypoxia and angiogenesis;PID BioCarta;100006

Pathway

phosphorylation of mek1 by cdk5/p35 down regulates the map kinase pathway;PID BioCarta;100210

Pathway

Signaling events mediated by Stem cell factor receptor (c-Kit);PID Curated;200156

Pathway

Natural killer cell mediated cytotoxicity;KEGG PATHWAY;hsa04650

Pathway

Endocytosis;KEGG PATHWAY;hsa04144

Pathway

Signaling in Immune system;Reactome;REACT:6900

Pathway

Signaling events regulated by Ret tyrosine kinase;PID Curated;200058

Pathway

igf-1 signaling pathway;PID BioCarta;100136

Pathway

Fc-epsilon receptor I signaling in mast cells;PID Curated;200003

Pathway

Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met);PID Curated;200032

Pathway

LPA receptor mediated events;PID Curated;200011

Pathway

calcium signaling by hbx of hepatitis b virus;PID BioCarta;100150

Pathway

il 3 signaling pathway;PID BioCarta;100128

Pathway

Focal adhesion;KEGG PATHWAY;hsa04510

Pathway

Chronic myeloid leukemia;KEGG PATHWAY;hsa05220

Pathway

EPO signaling pathway;PID Curated;200157

Pathway

T cell activation;PANTHER;P00053

Pathway

role of erk5 in neuronal survival pathway;PID BioCarta;100171

Pathway

Hepatitis C;KEGG PATHWAY;hsa05160

Pathway

PI3 kinase pathway;PANTHER;P00048

Pathway

map kinase inactivation of smrt corepressor;PID BioCarta;100032

Pathway

roles of beta arrestin dependent recruitment of src kinases in gpcr signaling;PID BioCarta;100230

Pathway

Insulin signaling pathway;KEGG PATHWAY;hsa04910

Pathway

VEGF signaling pathway;KEGG PATHWAY;hsa04370

Pathway

VEGF signaling pathway;PANTHER;P00056

Pathway

ErbB signaling pathway;KEGG PATHWAY;hsa04012

Pathway

p38 mapk signaling pathway;PID BioCarta;100085

Pathway

links between pyk2 and map kinases;PID BioCarta;100057

Pathway

Non-small cell lung cancer;KEGG PATHWAY;hsa05223

Pathway

t cell receptor signaling pathway;PID BioCarta;100022

Pathway

il 2 signaling pathway;PID BioCarta;100130

Pathway

GnRH signaling pathway;KEGG PATHWAY;hsa04912

Pathway

fc epsilon receptor i signaling in mast cells;PID BioCarta;100165

Pathway

Gap junction;KEGG PATHWAY;hsa04540

Pathway

the igf-1 receptor and longevity;PID BioCarta;100115

Pathway

integrin signaling pathway;PID BioCarta;100123

Pathway

Chemokine signaling pathway;KEGG PATHWAY;hsa04062

Pathway

Tight junction;KEGG PATHWAY;hsa04530

Pathway

cadmium induces dna synthesis and proliferation in macrophages;PID BioCarta;100209

Pathway

il 6 signaling pathway;PID BioCarta;100126

Pathway

Ras Pathway;PANTHER;P04393

Pathway

Acute myeloid leukemia;KEGG PATHWAY;hsa05221

Disease

Thyroid cancer;KEGG DISEASE;H00032

Disease

bladder cancer;GAD

Disease

Cancer;FunDO

Disease

anomalous connection of pancreatobiliary ducts;GAD

Disease

Squamous cell carcinoma;KEGG DISEASE;H00040

Disease

H-ras allele loss;GAD

Disease

Eating disorder;FunDO

Disease

Skin cancers;KEGG DISEASE

Disease

Bladder cancer;KEGG DISEASE;H00022

Disease

Actinic keratosis;FunDO

Disease

Herpes;FunDO

Disease

Thyroid carcinoma, follicular, somatic;OMIM

Disease

lung cancer;GAD

Disease

cervical cancer;GAD

Disease

Systemic scleroderma;FunDO

Disease

tumor progression of BCR/ABL negative chronic myeloproliferative disorders;GAD

Disease

Cancers of endocrine organs;KEGG DISEASE

Disease

Cancers of the digestive system;KEGG DISEASE

Disease

nodular type of malignant melanoma;GAD

Disease

colorectal carcinomas;GAD

Disease

Drug abuse;FunDO

Disease

PSYCH;GAD

Disease

Penile disease;FunDO

Disease

schistosomiasis;GAD

Disease

Hepatocellular carcinoma;KEGG DISEASE;H00048

Disease

Penile cancer;KEGG DISEASE;H00025

Disease

CANCER;GAD

Disease

Pancreas disease;FunDO

Disease

Cancers of the breast and female genital organs;KEGG DISEASE

Disease

Costello syndrome;OMIM

Disease

Cancers;KEGG DISEASE

Disease

Bladder cancer, somatic;OMIM

Disease

thyroid cancer;GAD

Disease

Cervical cancer;KEGG DISEASE;H00030

Disease

Cancers of the urinary system and male genital organs;KEGG DISEASE

Disease

breast cancer;GAD

Disease

Autism;GAD

Disease

patient prognosis A retrospective study of 103 cases;GAD

Disease

adenocarcinomas of the parotid gland;GAD

External Links

Links to cell senescence gene database

3265

Links to epithelial mesenchymal transition gene database

3265

Links to ovarian cancer gene database

3265

Links to endometrial cancer gene database

3265

Links to iHOP

3265

Sequence Information

Nucleotide Sequence

>3265 : length: 1251
TGCCCTGCGCCCGCAACCCGAGCCGCACCCGCCGCGGACGGAGCCCATGCGCGGGGCGAA
CCGCGCGCCCCCGCCCCCGCCCCGCCCCGGCCTCGGCCCCGGCCCTGGCCCCGGGGGCAG
TCGCGCCTGTGAACGGTGGGGCAGGAGACCCTGTAGGAGGACCCCGGGCCGCAGGCCCCT
GAGGAGCGATGACGGAATATAAGCTGGTGGTGGTGGGCGCCGGCGGTGTGGGCAAGAGTG
CGCTGACCATCCAGCTGATCCAGAACCATTTTGTGGACGAATACGACCCCACTATAGAGG
ATTCCTACCGGAAGCAGGTGGTCATTGATGGGGAGACGTGCCTGTTGGACATCCTGGATA
CCGCCGGCCAGGAGGAGTACAGCGCCATGCGGGACCAGTACATGCGCACCGGGGAGGGCT
TCCTGTGTGTGTTTGCCATCAACAACACCAAGTCTTTTGAGGACATCCACCAGTACAGGG
AGCAGATCAAACGGGTGAAGGACTCGGATGACGTGCCCATGGTGCTGGTGGGGAACAAGT
GTGACCTGGCTGCACGCACTGTGGAATCTCGGCAGGCTCAGGACCTCGCCCGAAGCTACG
GCATCCCCTACATCGAGACCTCGGCCAAGACCCGGCAGGGCAGCCGCTCTGGCTCTAGCT
CCAGCTCCGGGACCCTCTGGGACCCCCCGGGACCCATGTGACCCAGCGGCCCCTCGCGCT
GGAGTGGAGGATGCCTTCTACACGTTGGTGCGTGAGATCCGGCAGCACAAGCTGCGGAAG
CTGAACCCTCCTGATGAGAGTGGCCCCGGCTGCATGAGCTGCAAGTGTGTGCTCTCCTGA
CGCAGGTGAGGGGGACTCCCAGGGCGGCCGCCACGCCCACCGGATGACCCCGGCTCCCCG
CCCCTGCCGGTCTCCTGGCCTGCGGTCAGCAGCCTCCCTTGTGCCCCGCCCAGCACAAGC
TCAGGACATGGAGGTGCCGGATGCAGGAAGGAGGTGCAGACGGAAGGAGGAGGAAGGAAG
GACGGAAGCAAGGAAGGAAGGAAGGGCTGCTGGAGCCCAGTCACCCCGGGACCGTGGGCC
GAGGTGACTGCAGACCCTCCCAGGGAGGCTGTGCACAGACTGTCTTGAACATCCCAAATG
CCACCGGAACCCCAGCCCTTAGCTCCCCTCCCAGGCCTCTGTGGGCCCTTGTCGGGCACA
GATGGGATCACAGTAAATTATTGGATGGTCTTGAAAAAAAAAAAAAAAAAA

Protein Sequence

>3265 : length: 189
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPG
CMSCKCVLS