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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

2771

Name

GNAI2

Synonym

GIP|GNAI2B|H_LUCA15.1|H_LUCA16.1;guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2;GNAI2;guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2

Definition

GTP-binding regulatory protein Gi alpha-2 chain|adenylate cyclase-inhibiting G alpha protein|guanine nucleotide-binding protein G(i) subunit alpha-2|guanine nucleotide-binding protein G(i), alpha-2 subunit

Position

3p21.31

Gene Type

protein-coding

Pathways and Diseases

Pathway

Diabetes pathways;Reactome;REACT:15380

Pathway

Muscarinic acetylcholine receptor 2 and 4 signaling pathway;PANTHER;P00043

Pathway

Toxoplasmosis;KEGG PATHWAY;hsa05145

Pathway

Metabotropic glutamate receptor group II pathway;PANTHER;P00040

Pathway

Melanogenesis;KEGG PATHWAY;hsa04916

Pathway

Opioid Signalling;Reactome;REACT:15295

Pathway

Axon guidance;KEGG PATHWAY;hsa04360

Pathway

Leukocyte transendothelial migration;KEGG PATHWAY;hsa04670

Pathway

Signaling by GPCR;Reactome;REACT:14797

Pathway

CXCR3-mediated signaling events;PID Curated;200150

Pathway

PI3 kinase pathway;PANTHER;P00048

Pathway

5HT1 type receptor mediated signaling pathway;PANTHER;P04373

Pathway

Progesterone-mediated oocyte maturation;KEGG PATHWAY;hsa04914

Pathway

Thromboxane A2 receptor signaling;PID Curated;200069

Pathway

Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway;PANTHER;P00026

Pathway

Chagas disease;KEGG PATHWAY;hsa05142

Pathway

Gap junction;KEGG PATHWAY;hsa04540

Pathway

Hemostasis;Reactome;REACT:604

Pathway

Integration of energy metabolism;Reactome;REACT:1505

Pathway

Chemokine signaling pathway;KEGG PATHWAY;hsa04062

Pathway

Tight junction;KEGG PATHWAY;hsa04530

Pathway

Long-term depression;KEGG PATHWAY;hsa04730

Pathway

Gastric acid secretion;KEGG PATHWAY;hsa04971

Disease

Pituitary ACTH-secreting adenoma;OMIM

Disease

Cancers;KEGG DISEASE

Disease

Diabetes mellitus;FunDO

Disease

Adrenal carcinoma;KEGG DISEASE;H00033

Disease

CARDIOVASCULAR;GAD

Disease

Cancers of endocrine organs;KEGG DISEASE

Disease

Ventricular tachycardia, idiopathic;OMIM

Disease

blood pressure, arterial;GAD

External Links

Links to cell senescence gene database

2771

Links to epithelial mesenchymal transition gene database

2771

Links to ovarian cancer gene database

2771

Links to endometrial cancer gene database

2771

Links to iHOP

2771

Sequence Information

Nucleotide Sequence

>2771 : length: 2591
ACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTG
GGACTACAGGCGCCCGCTACCGCGCCCGGCTAATTTTTTGTATTTTTAATAGAGACGGGG
TTTCACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCGCCTTGGC
CTCCCAGAGTGCTGGGATGACAGGCGTGAGCCTCTGAGAGCAAATTTTACCCAGTTCCTC
TCTATCCTCCCGATGACTCTGAAATCAAACTCAGCAAGTCATCCGAGCCCCCACGGCGCA
GCGGCCCTAGGCTGGCATGGGCGATGCGGAGCTACTCCGCCCTCAGGAAGCAGGCGAGGT
GCCCAGCGGGAGAATCACCCACATCACCGTCTAATCTCTGCTGTGAAGTGGAAGCGCGAG
AAGGAGGGAGCGTCTCATGACGGAGGGTGTGAAGACGCTAGGCTGGACGAAGCAGAAAGG
CGGGTGTCACTGGGGACGTTCTGAGGGCCCCTGGTTGCTAAGGCTCAGTGTGGGGAGAAG
AAGGGCTGCTACCCTGTTGGATGGAGTATGCAGGGCATCTTCCTGCCAGCTCTGCCCAGG
GCACCATATTGGCATGCACCAGCTGCACAGGTGCTGGGGAGTCAGGGAAGAGCACCATCG
TCAAGCAGATGAAGATCATCCACGAGGATGGCTACTCCGAGGAGGAATGCCGGCAGTACC
GGGCGGTTGTCTACAGCAACACCATCCAGTCCATCATGGCCATTGTCAAAGCCATGGGCA
ACCTGCAGATCGACTTTGCCGACCCCTCCAGAGCGGACGACGCCAGGCAGCTATTTGCAC
TGTCCTGCACCGCCGAGGAGCAAGGCGTGCTCCCTGATGACCTGTCCGGCGTCATCCGGA
GGCTCTGGGCTGACCATGGTGTGCAGGCCTGCTTTGGCCGCTCAAGGGAATACCAGCTCA
ACGACTCAGCTGCCTACTACCTGAACGACCTGGAGCGTATTGCACAGAGTGACTACATCC
CCACACAGCAAGATGTGCTACGGACCCGCGTAAAGACCACGGGGATCGTGGAGACACACT
TCACCTTCAAGGACCTACACTTCAAGATGTTTGATGTGGGTGGTCAGCGGTCTGAGCGGA
AGAAGTGGATCCACTGCTTTGAGGGCGTCACAGCCATCATCTTCTGCGTAGCCTTGAGCG
CCTATGACTTGGTGCTAGCTGAGGACGAGGAGATGAACCGCATGCATGAGAGCATGAAGC
TATTCGATAGCATCTGCAACAACAAGTGGTTCACAGACACGTCCATCATCCTCTTCCTCA
ACAAGAAGGACCTGTTTGAGGAGAAGATCACACACAGTCCCCTGACCATCTGCTTCCCTG
AGTACACAGGGGCCAACAAATATGATGAGGCAGCCAGCTACATCCAGAGTAAGTTTGAGG
ACCTGAATAAGCGCAAAGACACCAAGGAGATCTACACGCACTTCACGTGCGCCACCGACA
CCAAGAACGTGCAGTTCGTGTTTGACGCCGTCACCGATGTCATCATCAAGAACAACCTGA
AGGACTGCGGCCTCTTCTGAGGGGCAGCGGGGCCTGGCGGGATGGGCCACCGCCGACTTT
GTACCCCCCAACCCCTGAGGAAGATGGGGGCAAGAAGATCACGCTCCCCGCCTGTTCCCC
CGCCGCTTTTCTCCTCTTTCCTCTCTTTGTTCTCAGCTCCCCCTGTCCCCTCAGCTCCAG
ACGTAGGGGAGGGGTTGCCACAGGCCTCCCTGTTTGAAGCCTGCCCTTGTCTGAGATGCT
GGTAATGGCCATGGTACCCCCTTCTGGGCATCTGTTCTGGTTTTTAACCATTGTCTTGTT
CTGTGATGAGGGGAGGGGGGCACATGCTGAGTCTCCCAAGGCTGCGTCTGGAGGGGCCCC
TGCTTCTCCAGCCTGGACCCCCAGCTTTGCCCAACACCAGCCCCTGCCCCAGCCCAAGTC
CAAATGTTTACAGGGAGCCTCCTGCCCAGTCCCCCAACCCCAGCCGCTCGGAGGCCCCAA
AGGAAAAAGCACAAGAAGCGTGAGACGCCACCATTCCTGGAAACCACAGTCCACCTGCTC
ATTCTCGTAGCTTTTTAAAAAAATGAAAGTAAAGGAAAAAAAAAAAACTGCAAATCTAGA
AAACTTTTTAGAGAAAAACTATTTAAAACTGTCAGATCCTGACCAGCAAGCCCCCCCCCA
GCCCCCCTTCCAAGTGACTCCGTGCCTTGAGTGTGTCTGCGTGTTTACACCCGTCCCTCT
GCTGGCCGCCCCCGTGCGAGCGGCACCCCTGCCCTGCCCTCCACAGAATTGGGTTCCAAG
GGCTGTTCCAGACAACTGCCAACGTCACTGAGGGCCCTGCCCCAGCGGCCCTGGCCCCAG
GCTCTATTAACCTAAAATGTAGCTCCCTAGCGCTAACCTAGGAACCGCCGCTGCCTGCTG
GGGGGCCACGCCCCTCATGCCCTTGTCCCAGGCCCGGGGCCTTCAGCGTTGAACACTTCC
TTGCTTTTTTCACATGTTTTATGGAATTGTTCACCTGGTTTGAAATAATAAAATGTAGAA
AGAAAAAAAAT

Protein Sequence

>2771 : length: 355
MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDG
YSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVL
PDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRV
KTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEE
MNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEA
ASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF