ONGene
Top
Scroll To Top
Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

22894

Name

DIS3

Synonym

2810028N01Rik|EXOSC11|KIAA1008|RRP44|dis3p;DIS3 exosome endoribonuclease and 3'-5' exoribonuclease;DIS3;DIS3 exosome endoribonuclease and 3'-5' exoribonuclease

Definition

DIS3 mitotic control homolog|exosome complex exonuclease RRP44|exosome component 11|mitotic control protein dis3 homolog|ribosomal RNA-processing protein 44

Position

13q22.1

Gene Type

protein-coding

Pathways and Diseases

Pathway

mRNA Decay by 3' to 5' Exoribonuclease;PID Reactome;500856

Pathway

Metabolism of RNA;Reactome;REACT:21257

Pathway

RNA degradation;KEGG PATHWAY;hsa03018

External Links

Links to cell senescence gene database

22894

Links to epithelial mesenchymal transition gene database

22894

Links to ovarian cancer gene database

22894

Links to endometrial cancer gene database

22894

Links to iHOP

22894

Sequence Information

Nucleotide Sequence

>22894 : length: 7589
GATGTTCCGAGGAGCGGAAAGCAACACACGTTGTGAGGTGGCGTCCAGAAGGAAGCCCCG
CCTAGGCCACGGGCGGAAATGGCTCCTCGCCTTGCTTTGCCGCCCCTCCCCACTCTCGCC
CAATCCCCGCGGCCGTCAGAGAGCCAACCAATGTTTATCTCGGCATTTTCCCGCGAGAAG
TGTTACTAATATCCGGGAATGGAAAGGGAAGAACCTCCGGGGTTAGGCGTATTCTAGATT
GACGCCTTTTGCTGGAAGAGCGCTGCTGGGGTTAGGATTCTGCGCGGCGAGGCAAGATGC
TCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCG
AGCACTACCTGCGAGACGACATCGGCTGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGG
CGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGAGCAGCGTCTGCCCGC
AACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGATGTTCTTGAGG
ACCCTGCCATCAGGAATGTAATTGTGCTACAAACAGTTCTTCAAGAAGTGAGAAATCGCA
GTGCCCCCGTATATAAACGCATCCGAGATGTGACTAATAACCAAGAGAAGCATTTCTATA
CTTTCACTAATGAGCACCATAGAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTA
ATGACAGGAATGATAGAGCGATTCGAGTAGCAGCAAAATGGTACAATGAACATTTGAAAA
AAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATGACAGGAGAAACAAAG
AGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAA
CTGCTAACCCCGAACTCATAGATCGTCTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAG
AAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGCTACAGCAAGGCATAA
AATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTA
CAGTATGGATTCATGGCGACAATGAAGAAAATAAAGAGATAATCTTACAGGGACTTAAAC
ATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTCTCCCCAAGAGTCAGT
GGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGA
AAGAAGAAGAGACAGAACGAATGCTTAAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTA
CAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATTGTGGCATGCTTTCCA
AGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTC
GAATTCGCATAGAAACCAGACAGGCTTCCACATTAGAAGGACGGAGAATTATTGTTGCTA
TTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTGTGAGAAATTTAGGTG
ATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATC
AGCCTTTTTCACAGGCTGTTCTTAGTTTTCTGCCAAAGATGCCCTGGAGCATTACTGAAA
AGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTAGTGTAGACCCACCAG
GATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGG
TTGGTGTTCATATTGCTGATGTGAGCCATTTTATTAGGCCAGGAAATGCCTTGGATCAAG
AATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGAGGATTGACATGGTTCCAG
AGTTGCTTAGCTCTAACTTGTGTTCCTTAAAATGTGACGTGGACAGGCTGGCATTTTCAT
GTATTTGGGAAATGAATCACAATGCTGAAATCTTAAAAACGAAGTTTACCAAAAGTGTTA
TTAATTCAAAGGCATCTCTGACGTATGCTGAAGCTCAGTTGAGAATTGATTCAGCAAACA
TGAATGATGATATTACCACTAGTCTCCGTGGACTGAATAAACTAGCCAAAATTCTGAAGA
AAAGAAGGATTGAAAAAGGGGCTTTGACTCTATCCTCTCCTGAAGTTCGATTCCACATGG
ACAGTGAAACTCACGATCCTATAGATCTGCAGACCAAGGAACTTAGGGAAACAAATTCCA
TGGTTGAAGAATTTATGTTACTTGCCAATATTTCTGTTGCAAAAAAAATTCATGAGGAAT
TTTCTGAACATGCTCTGCTTCGAAAACATCCTGCTCCACCTCCATCAAATTATGAAATTC
TTGTTAAGGCAGCCAGGTCAAGGAATTTGGAAATTAAGACTGATACAGCCAAGTCTTTGG
CTGAGTCTTTGGATCAGGCCGAATCTCCTACTTTTCCATATCTAAACACTCTGTTGAGAA
TATTAGCCACTCGCTGTATGATGCAAGCTGTGTACTTCTGTTCTGGAATGGATAATGATT
TTCATCACTATGGCTTAGCGTCTCCAATATACACACATTTTACTTCACCCATTAGAAGAT
ACGCAGATGTCATTGTTCATCGGCTTTTGGCTGTGGCTATTGGGGCTGACTGTACTTATC
CAGAGTTGACAGACAAACACAAGCTTGCAGATATATGTAAAAATCTAAATTTCCGGCACA
AAATGGCTCAATATGCCCAACGTGCATCAGTGGCTTTTCATACCCAGTTATTCTTCAAAA
GCAAAGGAATAGTAAGTGAAGAAGCCTATATTTTATTTGTAAGAAAGAATGCCATTGTGG
TATTAATTCCAAAGTATGGTTTAGAAGGGACAGTCTTTTTTGAAGAAAAGGACAAACCAA
ACCCACAGCTTATTTATGATGATGAGATACCCTCACTTAAAATAGAAGATACAGTGTTCC
ATGTATTTGATAAAGTTAAAGTGAAAATCATGTTAGACTCATCTAATCTTCAACATCAGA
AGATCCGAATGTCCCTGGTAGAACCACAGATACCAGGAATAAGCATTCCTACTGATACTT
CAAACATGGACCTTAATGGACCAAAGAAAAAGAAGATGAAGCTTGGAAAATAGCTATATT
CAACAAAAATCTTCAAAGACTGGTTTCTTTTTTAAAAGAAAAAACTTGAAAGAACACTTC
TAAGCCTAAGTGTGTGATACAGTTTGTTACTTTTAAGTACATTTTAATAATTTCAGACAT
CTGCATTTTTATTGAACAGTTGACTGTATCTGACCCATCATACTACTATACTTCTGGGTT
GAACAGAATTATTTATGCAGAATAATTCAATTGAATATCCATCACTTAAATACAGTGACA
GGACAGCAACTTCAGGGATCTGTAAAGATCATTTAAATGGAGTGCTCATCTCATTGAGGA
GCAGATTAATTTTGCGTAAGTACTTTGATTATTTAATATTTGTAAGAAAAAACTTTCATT
TTCCTACAGAGGAAAATAGAACAATTTTAGAAGCAAGGAACAATCTCTTTTCTAAGTCTT
GGAAGCTGTCAGTGTTGAGGATGTAATCTCCTTTGCCATCTTTAATTCACCTAACTTACA
CTAGGTGTTCTCTTACTGTCTTTAAAAGCTTCCTGTATTTTATTAGTGGTCCTTGAAAAA
CTGTGAATGTTTGGGAATTGGTAGAAAGGCAAAAAGTAGGATATTTTGACCTGACTGGAA
AGATGGTTGTGTTTTTATTGCCAGGTAATAAGTGTGATCATTGTTGAACTTCAGCTCCAG
TGTCTCTCCAGAATAAGACATTGGCATTCAAATGTCTATATCTTGTTACTTACAAAATAA
AAAACAGATTAATTAGTGGCTTTTAAATTGTAGTTATATCAGTGTATATACACGAGGGGA
ACTGTATAAAGACATACTAAAGGGAACAGATTAAAATAAGTATTATTAATAAAATTTGGT
GTGCCAGACTGACTACTTCCCTTGCTAATCACAGAGATTAGTAATGATTAAATTAATATC
TTCAGGAATATTTTGGGATAGGGTTGCCTTAAAACATTTTACTTGGCTTATTCAATTTCT
AAAGCACTTACGTTGTGCCAGGTTCCACTCAAGTAAATTATCTCTGCCTTCAAGGAGCTT
GCAGTATAGTGAGAAAAGCCTGCCAAGTAAATCAGCAGGTATACTAAATAGGTAGTCATT
TAGGCACTCAATAAATGTTGACTAATTTTTCCAGTTTCCTATTACTGAGGAAAACCTCCA
TACACTGAGGCAGAAACTTGTGTCAGTTGGAGGAAAATAGACTTGAGTAGTCTTTGGTCC
AGGTAAAATGGGTCAGTGACACTGAAACAGTAGAGTAGGAGTCAAAAAACCTTTTCTGTG
AAGTGCTAGAACATTTTAGACTTTGTTGGCTATGGTCTGTATTGCAACTATAGTACACAA
CTCTGCCGTTGATAGTGTGTAAGGAGCCATATACAATATGTAAACAAATCAACATGACTG
TGTTTCAACAAGGCCTGATTTGTTAAGTTTCATATATAGTCATATGTCACTTAATGACAG
GGATATGTTCTGAGACATGTCACTTGGCAATTTCATCATTGTGTGAAAATCATGATGTAG
TTACACAAACCTAGATGGTATACCCTATGGTATCCTATATGGGATAGCCTATTGCTCCTA
ACCTACAAACCTGTATGGCATATTACTGTACTGATTACTGTAGGCGGTTGTAACACAGTG
CTAAGTATTTGTGTATCTAAACATATCTAAACATAGAAAAGGTACAGTAAAAATATATAT
ATAGATATATATAAGATATAAAATGGTACACCTATTTAGGACATTTACCATGAACAAGTT
GGCAGGACTGGAAGCTGGCTCTGGGTGAGTCAGTAAGTGGTTAGTGAATGTGAAGGCCAT
GATATTACTGTGCACTACTGTAGACTTTTATAAACACTATATACTTAGGCTACATAAAGT
AATTTCACTATGATGTTACCATGGCTGTGTCCCCAGGCAATAGGAATTTTTCAGCTCCAT
TGTAATCTTACGGGATCATCATCGTATATTTGGCCATTGTTGACCAAAAGTTATGCAGCA
CATCATTATAATTTTGATGTGTCACAAAACATTACTCATTTGATTTCCCCCACCCCCGCC
AACCATTTAAAAAAGTTTGCCGGCTAGGTGCGGTGGCTCATGCCTGTAATCCTAGCATTT
TGGGAGGACGAGGCGGGTGGATCACTCGATGTCAGGAGTTTGAGACCAGCCTGGCCAACA
TGGTAAAACGCCGTCTCTACTAAAAATACAAAAACTTAGCTGGGTGTAACGGCGGATGCC
TGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCGGAA
GTTGCAGTGAGCCGAGATTGCACCACTGCAGTTCAGCCTGGATGATGAGAGTGAGACTCC
ATCGCAAAAAAAAAAAAAAAAAAAGAAAAGAAAATTAGCCAGGTGTGGTGGCAAGTGCCT
TTAATCCCACCTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCAGAGGTTG
CAGTGAGCCAAGATCGCGCCACTGCACTCCAGCCTGGGTGACAGAACAAGACTGTCTCAA
AAAAAAAAAAAGAGAAGAAAAACTGCCTACAGGCCATAGTTAACCTGCAATAGAGAAGAA
AGGGAAGTAGGGCAGTGCATGACTGGCCTTAGGTTTTTTCTTTCCAAGTTTATTTTCTTG
TGCTTCAGCTACTAGAAAGGTTTAATTCAGGGATAAGTCCCAATTGAGTAGTTCAAGATG
ATCAGAGACTTTGCTATTTTCCCCTAAGTTCTATTCCATAATCTAAAATGTTCTGTTTCT
AGTGCCAGTTCTTATGCTAAGCAGGTTACGTGGAATATATCACTTAACTCAAAAAGCCCT
GTTAAGCCAGGACTGTTATCTCCATTTAACAGATGAGAAAATGGAGGTTTATGGTCTGTT
CTCACACTGCTACGAAGAAATACCCCAAACTGGGTAATTATTATAAAGGAAAGAGGTTTA
ATGGACTCAGTTCCGCATTGCTGGTGAGGCCTCAGGACACTTACACAATCATGGCAGAAA
AAGGAGAAGCAGGCACCTTTTTCACAGGGCGGCAGGATGAAAATGACTGCCAGCAGTGGA
AATGCCAGACGCTTATAAAACCTTCAGATCTCATGAGACCGGCTCACTATCACAGGAACA
GCATGGAGGAAACCGCCCCCATGATCCAGTTACCTCCACCTGGTCCCACCCTTGACACGT
GGGGATTGCTACAATTCAAGGTTAGATTTGGGTGAGGACACAGAGCCATACCATATCAGC
CCAGATCAAGTAGTGACAGAGTAGGGATTTGAATACAGGTTATAGTCACTATTGTGTTAT
TTCTTGACTTTTGTACTATTAAAAAACTGTAGCCAGTGAGGCTTCTACCCTTAGTACCCA
GAACTCCTTTTAGGTATAGCAATTGTTTTTAGGTAAATTTATATTGAGTTTAACACCTGT
GTGATTAAAGACAACTTTCCAATGTAGTATCTGTAGCCATGTCCCCTAATGGCTATTAGT
GTTCATGGTTAGTGTGTTGAAGATGAGCCAGGTACATAACGCGGCACATTTTCTGCAGGT
CAGCAGTAAGGTTTCAAGGTACAGTTATGGAGGAAAGAAGAAAATGACACATTGATAACA
CAGGTCTTTATTCCCTTTTGAATGAGACAGTTTTTAAAAGTTGATTTATAAATACAAAAA
TACATTCTCCAAAGATAGTATTTCCAAACTGTTATATACCCATCTACTCCCAACATGGAT
ATAAGTTTTTTAAAAAAATAGTTGTATATAACATACATATCTGCCCCAGTGTTACTTCAC
AGGCCTATGCCCTACGGGAACTCCACTCTCCCAGCCCCACTTTTTCTCTTGGTTCTCCCA
CATTCTTATTCTCCCACATCCCTACCCACGTTTGAGCTGGAAAGGATGTCCCTACCCTAG
GCATGAGGTATATTTTATTCTGGGCACCACACATTTGCCCCATAGATAACAATACACGTG
ATGATGTCACTAGTACTACCTTTCTAGTATTTACATACTTAAAAGTAGTAACTAGAACAG
TTATCACTGGAACTAAGAATTTTCCCCACAGAGGTGAACAGACCAAGAACTAAAATTTCA
GGAAACCTGTTTAATTTCTTTTGTATCTTTGAAAAGTTAGTTTTATATCTAAGATTTCTT
CACATAGGTTATAATTCATCTGTATGTTCAAGCTTTTATGTAAAAATATATAGTGCCTTC
AGTTTTAACATAGTTTCACATGTTCTCAGAACTGCTAAATTCAGTGCTACCAGTAAGGCT
TAATAAGTAGTTCATTGACCCTGTAAGATAGGAGCACTCAGCTCTGTCACAATTTGTTGT
TAAACACATCACTCAATGTAAGTATAAAAATATTTATTGATAAAAAATAAACTTATAATT
CAGCAAAAAAAAAAAAAAAAAAAAAAAAA

Protein Sequence

>22894 : length: 958
MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVC
PQPHYLLPDTNVLLHQIDVLEDPAIRNVIVLQTVLQEVRNRSAPVYKRIRDVTNNQEKHF
YTFTNEHHRETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRN
KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQG
IKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKS
QWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML
SKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNL
GDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP
PGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKRIDMV
PELLSSNLCSLKCDVDRLAFSCIWEMNHNAEILKTKFTKSVINSKASLTYAEAQLRIDSA
NMNDDITTSLRGLNKLAKILKKRRIEKGALTLSSPEVRFHMDSETHDPIDLQTKELRETN
SMVEEFMLLANISVAKKIHEEFSEHALLRKHPAPPPSNYEILVKAARSRNLEIKTDTAKS
LAESLDQAESPTFPYLNTLLRILATRCMMQAVYFCSGMDNDFHHYGLASPIYTHFTSPIR
RYADVIVHRLLAVAIGADCTYPELTDKHKLADICKNLNFRHKMAQYAQRASVAFHTQLFF
KSKGIVSEEAYILFVRKNAIVVLIPKYGLEGTVFFEEKDKPNPQLIYDDEIPSLKIEDTV
FHVFDKVKVKIMLDSSNLQHQKIRMSLVEPQIPGISIPTDTSNMDLNGPKKKKMKLGK