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Gene information | Literature | Expression | lncRNA | Mutation | Homolog

Basic Information

Gene ID

1399

Name

CRKL

Synonym

v-crk avian sarcoma virus CT10 oncogene homolog-like;CRKL;v-crk avian sarcoma virus CT10 oncogene homolog-like

Definition

crk-like protein

Position

22q11.21

Gene Type

protein-coding

Pathways and Diseases

Pathway

il-2 receptor beta chain in t cell activation;PID BioCarta;100129

Pathway

Fc gamma R-mediated phagocytosis;KEGG PATHWAY;hsa04666

Pathway

Neurotrophin signaling pathway;KEGG PATHWAY;hsa04722

Pathway

Regulation of actin cytoskeleton;KEGG PATHWAY;hsa04810

Pathway

MAPK signaling pathway;KEGG PATHWAY;hsa04010

Pathway

PDGFR-alpha signaling pathway;PID Curated;200140

Pathway

Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met);PID Curated;200032

Pathway

Bacterial invasion of epithelial cells;KEGG PATHWAY;hsa05100

Pathway

Signaling by PDGF;Reactome;REACT:16888

Pathway

Focal adhesion;KEGG PATHWAY;hsa04510

Pathway

Chronic myeloid leukemia;KEGG PATHWAY;hsa05220

Pathway

Pathways in cancer;KEGG PATHWAY;hsa05200

Pathway

Reelin signaling pathway;PID Curated;200051

Pathway

Neurotrophic factor-mediated Trk receptor signaling;PID Curated;200128

Pathway

Shigellosis;KEGG PATHWAY;hsa05131

Pathway

IFN-gamma pathway;PID Curated;200110

Pathway

inhibition of cellular proliferation by gleevec;PID BioCarta;100154

Pathway

Insulin signaling pathway;KEGG PATHWAY;hsa04910

Pathway

ErbB signaling pathway;KEGG PATHWAY;hsa04012

Pathway

links between pyk2 and map kinases;PID BioCarta;100057

Pathway

angiotensin ii mediated activation of jnk pathway via pyk2 dependent signaling;PID BioCarta;100236

Pathway

Angiogenesis;PANTHER;P00005

Pathway

Integrin signalling pathway;PANTHER;P00034

Pathway

IGF1 pathway;PID Curated;200084

Pathway

Paxillin-independent events mediated by a4b1 and a4b7;PID Curated;200178

Pathway

Renal cell carcinoma;KEGG PATHWAY;hsa05211

Pathway

Signaling in Immune system;Reactome;REACT:6900

Pathway

integrin signaling pathway;PID BioCarta;100123

Pathway

Chemokine signaling pathway;KEGG PATHWAY;hsa04062

Pathway

EPO signaling pathway;PID Curated;200157

Pathway

Paxillin-dependent events mediated by a4b1;PID Curated;200117

Pathway

Signaling events mediated by Stem cell factor receptor (c-Kit);PID Curated;200156

Disease

Leukemia;FunDO

Disease

Influenza;FunDO

External Links

Links to cell senescence gene database

1399

Links to epithelial mesenchymal transition gene database

1399

Links to ovarian cancer gene database

1399

Links to endometrial cancer gene database

1399

Links to iHOP

1399

Sequence Information

Nucleotide Sequence

>1399 : length: 5336
CGGAGGGGGAGGTGGCTGCCGCTTCTCCCGCGTCCGCCATTTTGTTGCTGTGGCTATTGG
GAACAAGCTGGGCAAAAGCACCCCGGAGGCGCGACGCTCCTTCGAGTTCGGTGCCTCGTG
TGACGGCGGGGGTCGGTGAAGACCCGTCGAGCTGCGGCGCCGGCGCGTTCCAGGCCGGGA
GTCACTGGAGGCACCCCTGGGACGCCGAGCAGCCCGAGAACCCCGGGGTGGCCTCCGCTG
CGGCTCGGGTTTGCCTGCCCCGACCCCCCGGCTCTGCCGTGCATTCCCGGGCGGCTCTCT
CCGTGTGGCGGCCCCGGAGCAGGCGGGCGGCGTCGGAGGATGCTGCGGGCCCGGAGCCGA
GAGGAAAGTGCTGGCCCAGCCCTCTGAGCGCTCCTCGAGGTGTGCGAGAGGCCCTTCCTC
GGCCCCAAAGCCGTCTGCCGGGCTAAGGCGTGCAGAGCAGGCGAGGACAGCCGCCGCCCC
TACCGCCGCAGAGTCCCCGGTCCAACACCATGTCCTCCGCCAGGTTCGACTCCTCGGACC
GCTCCGCCTGGTATATGGGGCCGGTGTCTCGCCAGGAGGCGCAGACCCGGCTCCAGGGCC
AGCGCCACGGTATGTTCCTCGTCCGCGATTCTTCCACCTGCCCTGGGGACTATGTGCTGT
CGGTGTCCGAGAACTCGCGGGTCTCCCACTACATCATCAACTCGCTGCCCAACCGCCGTT
TTAAGATCGGGGACCAGGAATTTGACCATTTGCCGGCCCTGCTGGAGTTTTACAAGATCC
ACTACCTGGACACCACCACCCTCATCGAGCCTGCGCCCAGGTATCCAAGCCCACCAATGG
GATCTGTCTCAGCACCCAACCTGCCTACAGCAGAAGATAACCTGGAATATGTACGGACTC
TGTATGATTTTCCTGGGAATGATGCCGAAGACCTGCCCTTTAAAAAGGGTGAGATCCTAG
TGATAATAGAGAAGCCTGAAGAACAGTGGTGGAGTGCCCGGAACAAGGATGGCCGGGTTG
GGATGATTCCTGTCCCTTATGTCGAAAAGCTTGTGAGATCCTCACCACACGGAAAGCATG
GAAATAGGAATTCCAACAGTTATGGGATCCCAGAACCTGCTCATGCATACGCTCAACCTC
AGACCACAACTCCTCTACCTGCAGTTTCCGGTTCTCCTGGGGCAGCAATCACCCCTTTGC
CATCCACACAGAATGGACCTGTCTTTGCGAAAGCAATCCAGAAAAGAGTACCCTGTGCTT
ATGACAAGACTGCCTTGGCATTAGAGGTTGGTGACATCGTGAAAGTCACAAGGATGAATA
TAAATGGCCAGTGGGAAGGCGAAGTGAACGGGCGCAAAGGGCTTTTCCCCTTTACGCACG
TCAAAATCTTTGACCCTCAAAACCCAGATGAAAACGAGTGATTGCTGTTGCCCTGTTTCC
TGCTGCTTTGTTGTTCTGCCTGTCCTAGTCTCCTTTGAAGTGGGAAAGCATTTTCTCTCA
TAGGCAAGTCACACTGCATTGCCGAAGTCCAGCTTTCTGCAGACTGGCAGTCGCACACAC
ATTTGGAATGCACACAGCGGCTGCCTCCTGATGTTTGTATCATAGTCGTATTGTCAAAGA
GTAGCCGATTTTAGAGTTCTTTTGGATCATAAACTGGAAATACTGATGGAAGCACACAAG
TGGAGAGAAGTTGACATGGAAAGGGTCTTCCTTCTCATTGCTGCCCGTTTGTACATGGGA
CTGATTCTGTTGTGTTCACCAGAGAAAGCTTGAGGCCATGGCGAGATACTGCATGTTTGC
TGTTCCACAAAGCAGTGGCTTAGCTGCCATCTTGCTTTTCTTTGGACAACAGGAAGTGAA
CCTTAAGGAAGAGAGAATTCTGTTCTAAAACTCCAAAATCTGGCTTTTTTTTTTCTTTTG
TTTTGGTTTGGTTTTGGAAAACTAATTAATTAGACTTGTGTGGGGGTTTTTTTTTGTTTT
GTTTTGTTTGTTTTGTTTTGTTTTTTTGAGACGGTGTCTCGCTGCATCACCCAGGCTGGA
GTGCAGTGGCGCAATCTCGCCTTCCTGCAGTCTCCGCCTCCTGAGTTCAAGCGATTCTCC
TGCCTCAGCCTCCCAAGTAGCTGGGACTGCAGGCGCGCACACCACGCCCAGCTAATTTTT
GTATTTTTAGTAGAGACGGGGTTTCATCATGTTGACCAGGCTGGTCTCAAACTCCTGACT
TCAGGTGATCCACCCGCCTTCAGCCTCCCAACGTGCTGGGATTACAGCCGTGAGCCGCCG
CGCCTGGCCTAGACTTGTGTGTTCTAAACAGGTTAAGTAGCAGGTTGGGTTTTTATGATA
GTGCAAGGAATGACTCATGCCTCTGAGCTTCTAAACTGAAGCTGCTGTAACTAAAGGAAT
CTGAAAAGAACAACCCTGAAGCAGAGGCCTTTATTGTCTTGGTTGCCAGTAGTACCTTGT
TTTGCCATGTAGCAGACAACACACAAAATAATGCAGTTGTGGTGTGCCATGCTATGTGCA
CAGCCCCTTGGATTACTTTGTTTTAAAAAGCATCAGAGTTGGGGGTACTTTAGGGAAACC
TTTGCTTACCTTGTTTTGCCAGTGATAAGAGCAGTGGGTTGGAGGGCACTTGGCCAGTTT
TCTGTTCAGCTTTTCAGTGAATGTACCCCTTTAAGGTTCAGACTTAAACTTCCTTAAAAA
GTGGCGTTGTTCATAGAATCGTTGGACTCATTAATGAATCGTTCAACTCCACTCACTGAA
GCCCAGACCTCCGTGCCCAGGCCCAATCTCGTCAGGCTGCCAGAGAAAGTTGGTGCTGCT
CATACTGGTCTCACAGTCTAAGTAAGTGTCTGTGATGCTCCCAAGCAAAGGAAATGCAAG
CTCTGGAAATTCGTTAATGTATTTGATGTCTTAGTGTTTTAGTGACTAGGGAGACCATTA
ACTAGTTTATCATTAACCACTTATCAGTGTATTGATGTTAAAGCATTTCCCTGTTAGCTA
AAAGAGGCCTGTTCATACAAGCCAACTGGTATATACGTGTGGTTCATCCATCATCTGCTG
CACATAGCAGACTAGAATTCTGGGAACCCTGTGCAATTCAGTCTGCTCTCCCTTGTGGAC
CCTGGTAAAGAAAAGCCTCAGCTCATAGTGAACACAGCAGACCTAGAAATGTAGCAGCAG
CCTACTGAGTAGCTTTCATTTACTGATCATCTGCTGTGACTGTGGCCCTGTCTGGAGGTT
CCTAGGTTTTGAGATTTAGAGCAATGCATTCTGGAGACAGAACCAGCAGAACAGCCATTT
TTCAATTTTTCTTTAAATCAGTATTCCATCAGGCAGATAACTGCTGTATTCATGAATCTT
GAGAGTGTTCCTGAGACAGAATTAATGGTCATTTGGGAAAACTATCGCCATGGCTTCCCA
TCTGTGGTTTTCCTCTAAAAGCCTTGGAGATTAGCCCTTCCTTGCCAGTGAGAACGGTGA
CCGCCTCCTGCTCTGCACGGTCTGCGGCAGTTGCCGCTTCTGGTTAGGTGTGTCAGGTTG
GCTTATTTTGGGTTCAGGCCTGGCGTAGCACCCACAAGTGGCAGACATATCACAAGAGTC
CCCAGACTCTGCCTAGAAACAGTGTTTGCCCTTTGGCCAGTGACGTGGTTCATCCCGGCC
CATGTTGAGCCATGAGTGGAGTTTCCAACAGAGGGAGGAATGTGTGCCTTGTTCAAGGAG
GGCACGACCCTTAGGCCTTTTTCAACCAGATTTAGCTGAAGGGCTTGACACCTTTGAATT
ACAGCAGTTGACTCAGAGTGCAAGAAGTCTGGCCATTTTGGAAAGCAAGGTTTCCTTTCA
GCCCTGTCTACTGACCAATACCCCGACTCACCTTGTGTGGCGCACTTCAGAATCAGATAT
ACCTAGAGTATACCTGTGGTTTGGTTTTATAATTAATCAGCTCGTTACTTCAGCCCATGA
AAATGGCATCCAGGGCTGCCAGGAGATTCAGAGCTCAAAACAAGGCGAGCTTGAGTTCTG
CACTCCAGATATGTGCCAAAACTAGTAAAACTTAACGGACTTACAACCTTGTCAGTTTTT
TTAATGAGGCAGGGATACTCTGTTTTTCACACTAAACATATGAATGCAGCACTGCTGCCT
CAGCTCAGCTTCGTGCCTGGGTTCCCCACTGGTCTGGGAAGACTGTTGTGCTCCATAGAG
CAGTGCACATCTGACCCAGAGGGTGGGTGTTCATAACTGCTACTTGCTCTGCTCTACCAT
GTTTAAAGAAATATTTGGATGTTAAATTAACTCACTATGGTTTTTCACCTGGGAAGGAAA
CAAATTACGTACTAGAGGGCATTGACTGGTTAAAAACTTGTGTATCCCGGGAAGGACCTG
CGGTACAGGAGTCAGCCATGTCTGTGCTGTGTGGAACCACCTGATGACATGGTTAACGAG
GAAGACGATGTGTTGACCGGCTGCCGTTTGAGGACTTTGGTCACCCAGACTAGACACCTT
CTGTGCTCATGTTTGGAAAGCTGAAAGGGAAGGACAGCTGTGCCCTCCTGGGAGCTCATG
TGTCCCTGGCGCTGTGCTAGCTTTCCTTTACAGCTGTTTACAGACAAGGCAGGCCTGAGG
CAGATGGCCACTGCTCTTGTGATGTTTGCTCAGAGGAATATGAACATTTTATTTTTGAAA
AGGGATGATGTGGTTTTTTGCCAGGTGTTTATAATTAATCCTTTAATATTATGGTTATTA
ACCTCTTAAACATGAATGAATTCTTGATTGTTTTAACACAGTACCTAAGACTAATGCTTT
CTGTGGACACCACTGAGCTCTGCCTCAACTCCACCCTCTGCGACCGGAGGACTATGCCCC
TAGTAACTGCTGTCGGTGTGGACGCTGTGCTGGTTCTGTTTTCTAAAGGAGCAGAAGGAC
AGGTCTCTGAGACAGGATCGTTGTCCCTACAGGAGGAACAGTGGCCTTGCTTCTTAGACG
GTCTTCACTGTGTGTTTTAAAACAACAACAACAACAACAACAACAACATAAAACTCTTTT
GACCTGTAACTTAAAGATCATAAACTTCAGGCAATAATATTTTCTGTGTAAGCTTTTAAA
ATTATTTTTGGGGATCATAGCTTGTTTTATTTTGTGCTATAAAATTAACAGTATTAAATG
ACTTATATTCTTAGAATACATCGAGTGTCTTTTCTTAACAGATTAGTGCCTTTTTATTTT
TGTATTCCGTTTTACGTTACTGGTCCCAGCATCAAAACCCTTGTTTCCATGGCCTGTTTG
TATATTGTCTCAATAAAACTTGCATCAGCCGGTGGTGGCGGCAGCAAAAAAAAAAA

Protein Sequence

>1399 : length: 303
MSSARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSH
YIINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDTTTLIEPAPRYPSPPMGSVSAPNLPT
AEDNLEYVRTLYDFPGNDAEDLPFKKGEILVIIEKPEEQWWSARNKDGRVGMIPVPYVEK
LVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQNGPVFA
KAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLFPFTHVKIFDPQNPD
ENE